glutathione pentose phosphate pathway in Growth & Antioxidant Defense Acute Activation of Oxidative Pentose

doi: 10.1016/j.jnutbio.2013.11.009 90 AltmanBJStineZEDangCV

Your medical history, current kidney and liver function, and other medications all play a role in determining what is safe for you

This study was supported by National Natural Science Foundation of China (82205102, 82174362)

As the original source of ATMs, this phenomenon also provides a certain basis for the possibility of ferroptosis of ATMs

R This pathway is the primary defense against: Aflatoxin B1 (a carcinogenic mycotoxin produced by Aspergillus) Cadmium Epoxides (reactive Phase I intermediates from polycyclic aromatic hydrocarbons) Lipid peroxidation products (4-hydroxynonenal, malondialdehyde) Mercury (organic and inorganic forms) Reactive oxygen species (ROS) and reactive nitrogen species (RNS) GSTs exist in three locations: cytosolic (the largest class, with alpha, mu, pi, theta, sigma, omega, and zeta subfamilies), mitochondrial (kappa class), and microsomal (MAPEG family)